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Christian Habeck, PhD

  • Associate Professor of Neuroimaging (in Neurology and the Taub Institute for Research on Alzheimer's Disease and the Aging Brain) at CUMC
Christian Habeck, PhD

Dr. Habeck originally trained as a Particle Physicist in the UK, completing this studies with a PhD in 1998 from the University of Sussex. During the last years of his graduate training he became interested in the Neurosciences, leading him to move to the Neurosciences Institute in San Diego in 1998, spending 2.5 years pursuing large-scale neural networks models of the cat thalamocortical system as Postdoctoral Fellow under the guidance of Gerald Edelman. In 2000, Dr. Habeck moved to Columbia University and joined the Cognitive Neuroscience Division of the Taub Institute. He specializes in multivariate data analysis of PET and fMRI brain imaging data for the purposes of basic research and early detection of Alzheimer’s Disease. His general interests concern robustness and replication of empirical inference in neuroimaging.

Departmental Appointments

  • Department of Neurology
    Division of Cognitive Neuroscience

Languages Spoken

(in addition to English)

  • German

Centers/Institutes/Programs

  • Gertrude H. Sergievsky Center
  • Taub Institute for Research on Alzheimer's Disease and the Aging Brain

Past Positions

Postdoctoral/ Associate Research Scientist/Assistant Professor
Columbia University Medical Center
 
Junior Fellow
The Neurosciences Institute
Greater San Diego Area

Computational neuroscience

 

Teaching Responsibilities

  1. Fall Term 2011: G4222 Seminar: “The  cognitive neuroscience of aging”, Department of Psychology, Columbia University
  2. Fall Term 2012: G4222x Seminar: “The  cognitive neuroscience of aging”, Department of Psychology, Columbia University
  3. The Art and Pitfalls of fMRI pre-processing” – Half-Day Educational Course, Organization for Human Brian Mapping, Annual Meeting, 2014, Hamburg, Germany
  4.  Fall Term 2014: G4222x Seminar: “The  cognitive neuroscience of aging”, Department of Psychology, Columbia University
  5. The Art and Pitfalls of fMRI pre-processing” – Half-Day Educational Course, Organization for Human Brian Mapping, Annual Meeting, 2015, Honolulu, USA

Committees/Societies/Memberships

Society for Neuroscience

Organization for Human Brainmapping

Honors & Awards

NIH/ NIBIB RO1EB006204 04/01/07 -03/31/10
Multivariate approaches to Neuroimaging Analysis
Role: PI


NIH/NIA 1R01AG026114-01A2 09/01/07-06/30/12
Early AD Detection with ASL MRI & Covariance Analysis
Role: PI

Research Interests

  • Multivariate analysis of clinical and basic neuroimaging data
  • Robustness analysis of pre-processing in functional MRI
  • Development of neuroimaging-based biomarkers for aging, psychiatric and degenerative disease

NIH Grants

  • IMAGING OF COGNITION, LEARNING AND MEMORY IN AGING (Federal Gov)

    May 1 2017 - Mar 31 2022

    EXPLORING COGNITIVE AGING USING REFERENCE ABILITY NEURAL NETWORKS (Federal Gov)

    Aug 1 2016 - Jun 30 2021

    BENFOTIAMINE IN ALZHEIMER S DISEASE: A PILOT STUDY (Federal Gov)

    Sep 1 2014 - May 31 2019

    EXAMINATION OF THE EARLIEST SYMPTOMS AND BIOMARKERS OF FTLD MAPT CARRIERS (Federal Gov)

    Sep 21 2012 - Jul 31 2018

    IMAGING STIMULANT EFFECTS ON EMOTIONAL LIABILITY IN CHILDREN WITH ADHD (Federal Gov)

    Aug 16 2013 - May 31 2018

    EXERCISE, AGING, AND COGNITION: EFFECT AND MECHANISMS (Federal Gov)

    Aug 1 2010 - May 31 2017

    PROTECTION AGAINST COGNITIVE DECLINE IN MS: LONGITUDINAL INVESTIGATION OF RESERVE (Federal Gov)

    Jul 11 2016 - Apr 30 2017

    EPIDEMIOLOGY OF BIOMARKERS OF RISK AND PROGRESSION IN LOAD (Federal Gov)

    May 1 2010 - Apr 30 2017

    BENFOTIAMINE IN ALZHEIMER S DISEASE: A PILOT STUDY (Private)

    Jan 1 2015 - Dec 31 2016

    MULTIMODAL IMAGING OF THE MESOCORTICAL SYSTEM I ANOREXIA NERVOSA (Federal Gov)

    Jan 13 2014 - Dec 31 2015

    EARLY AD DETECTION WITH ASL MRI & COVARIANCE ANALYSIS (Federal Gov)

    Sep 1 2007 - Jun 30 2014

    INVESTIGATION OF THE DOPAMINE SYSTEM IN FRONTOTEMPORAL DEMENTIA (Federal Gov)

    May 1 2009 - Apr 30 2014

    MEDITERRANEAN DIET AND OTHER DIETARY PATTERNS IN ALZHEIMER S DISEASE (Federal Gov)

    Mar 1 2008 - Feb 28 2014

    METABOLIC ADAPTATION AND CHANGES IN CENTRAL NERVOUS SYSTEM CIRCUITRY IN WEIGHT-PERTURBED C57BL/6J MICE (Private)

    Jun 16 2008 - Nov 30 2013

    VASCULAR DEPRESSION IN AA: PHENOMENOLOGY, TREATMENT, AND COURSE OF ILLNESS (Federal Gov)

    Jul 1 2010 - Jun 30 2013

    MULTIVARIATE APPROACHES TO NEUROIMAGING ANALYSIS (Federal Gov)

    Apr 1 2007 - Jan 31 2011

Publications

  1.  

    Habeck C, Risacher S, Lee GJ, Glymour MM, Mormino E, Mukherjee S, Kim S, Nho K, DeCarli C, Saykin AJ, Crane PK; Alzheimer’s Disease Neuroimaging Initiative. Relationship between baseline brain metabolism measured using [¹⁸F]FDG PET and memory and executive function in prodromal and early Alzheimer's disease. Brain Imaging Behav. 2012 Dec;6(4):568-83. doi: 10.1007/s11682-012-9208-x. PubMed PMID: 23179062; PubMed Central PMCID: PMC3532575.
  2. Habeck C, Steffener J, Rakitin B, Stern Y. Can the default-mode network be described with one spatial-covariance network? Brain Res. 2012 Aug 15;1468:38-51. doi: 10.1016/j.brainres.2012.05.050. Epub 2012 Jun 2. PubMed PMID: 22668988; PubMed Central PMCID: PMC3430376.
  3. Habeck C, Rakitin B, Steffener J, Stern Y. Contrasting visual working memory  for verbal and non-verbal material with multivariate analysis of fMRI. Brain Res. 2012 Jul 27;1467:27-41. doi: 10.1016/j.brainres.2012.05.045. Epub 2012 May 28. PubMed PMID: 22652306; PubMed Central PMCID: PMC3398171.
  4. Habeck C, Moeller JR. Intrinsic functional-connectivity networks for diagnosis: just beautiful pictures? Brain Connect. 2011;1(2):99-103. doi: 10.1089/brain.2011.0021. Review. PubMed PMID: 22433005.
  5. Habeck CG. Basics of multivariate analysis in neuroimaging data. J Vis Exp. 2010 Jul 24;(41). doi:pii: 1988. 10.3791/1988. PubMed PMID: 20689509; PubMed Central PMCID: PMC3074457.
  6. Habeck C, Stern Y; Alzheimer’s Disease Neuroimaging Initiative. Multivariate data analysis for neuroimaging data: overview and application to Alzheimer's disease. Cell Biochem Biophys. 2010 Nov;58(2):53-67. doi: 10.1007/s12013-010-9093-0. Review. PubMed PMID: 20658269; PubMed Central PMCID: PMC3001346.

For a complete list of publications, please visit PubMed.gov