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Darryl C. De Vivo, MD

  • Sidney Carter Professor of Neurology
  • Professor of Pediatrics
  • Founding Director, Colleen Giblin Research Laboratories for Pediatric Neurology
  • Associate Chairman, Pediatric Neurosciences and Developmental Neurobiology
  • Co-Director, Motor Neuron Center
  • Director, Spinal Muscular Atrophy (SMA) Center
  • Chief Emeritus, Pediatric Neurology
Darryl C. De Vivo, MD

Dr. Darryl C. De Vivo, M.D., is the Sidney Carter Professor of Neurology, Professor of Pediatrics, and Director Emeritus (1979-2000) of the Pediatric Neurology Service at Columbia University Medical Center in New York City. Dr. De Vivo received his M.D. Degree from the University of Virginia Medical School. Residency training in Medicine, Pediatrics, Neurology and Pediatric Neurology followed at Harvard, National Institutes of Health and Washington University. He then joined the Medical School Faculty at Washington University and over the next decade was promoted from Assistant Professor to Professor as he developed his clinical research skills in neurochemistry, metabolic diseases and neuromuscular disorders. He joined the Columbia University Faculty in 1979 as the Sidney Carter Professor of Neurology and Pediatrics and Director of the Pediatric Neurology Service. Currently he continues to fulfill his duties as Founding Director, Colleen Giblin Research Laboratories; Director, Pediatric Neuromuscular Disease Center, Co-Director of the Center for Motor Neuron Biology and Diseases (MNC) and Associate Chairman (Neurology) for Pediatric Neurosciences.  Dr. De Vivo was a Director for Neurology and President of the American Board of Psychiatry and Neurology, Secretary of the American Academy of Neurology, and President of the Child Neurology Society. He has published more than 450 original articles and reviews, lectures extensively in the U.S. and abroad, serves on several editorial boards and advisory committees, and is a former associate editor for Rudolph's Textbook of Pediatrics. He is a current editor of "Neuromuscular disorders in Infancy, Childhood and Adolescence: A Clinician's Approach", recognized as the standard reference in the field. Dr. De Vivo receives funding from the NIH, DOD, SMA Foundation, MDA, Colleen Giblin Foundation, Milestones for Children and the Will Foundation. He serves as the Director for the PNCR Clinical Trials Network for SMA.

Research Interests: Genetically-determined metabolic diseases that affect the developing brain and neuromuscular system. Specific disorders include Glut1 deficiency, mitochondrial diseases, epilepsy, Duchenne muscular dystrophy, Spinal Muscular Atrophy (SMA) and other pediatric neuromuscular diseases.

Clinical Interests: Child neurology, neuromuscular disorders, neurometabolic disorders, and neurogenetics.

Departmental Appointments

  • Department of Neurology
    Division of Child Neurology
  • Department of Pediatrics

Board Certifications

  • Child Neurology
  • Neurology with Special Qualification in Child Neurology

Areas of Expertise

  • Child Neurology
  • Neurology With Special Qualifications In Child Neurology
  • Pediatric Neuromuscular Disease
  • Mitochondrial Diseases
  • Neurometabolic Disorder
  • Pediatric Epilepsy

Education & Training

  • University of Virginia School of Medicine
  • Residency: National Institutes of Health
  • Residency: Massachusetts General Hospital
  • Fellowship: Washington University Medical Center

Locations

  • Neurological Institute of New York

    710 West 168th Street
    Floor: 2, Room: 201
    New York, NY 10032
    Phone:
    (212) 305-5244
    For new and current patient appointments, call:
    (212) 305-5244
    Fax:
    (212) 305-7036
  • Harkness Pavilion

    180 Fort Washington Avenue
    Floor: 5
    New York, NY 10032
    Phone:
    (212) 305-5244
    Fax:
    (212)305-7036

Centers/Institutes/Programs

  • Colleen Giblin Research Laboratories
  • Motor Neuron Center
  • Spinal Muscular Atrophy Center

Provider Affiliations

  • NewYork-Presbyterian/Columbia

This provider sees pediatric patients

This provider accepts new patients

Appointment Phone Number: (212) 305-5244

Research Interests

  • Research interests include genetically-determined metabolic diseases that affect the developing brain and neuromuscular system. Specific disorders include Glut1 deficiency, mitochondrial diseases, epilepsy, Duchenne muscular dystrophy, Spinal Muscular Atrophy (SMA) and other neuromuscular diseases.

NIH Grants

  • MITOCHONDRIAL ENCEPHALOMYOPATHIES: APPROACHES TO TREATMENT (Federal Gov)

    Sep 30 2014 - May 31 2019

    A RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED, PARALLEL-GROUP, ADAPTIVE STUDY TO ASSESS THE SAFETY AND EFFICACY OF UX007 IN SUBJECTS WITH GLUCOSE TRANSPORTER TYPE 1 DEFICIENCY SYNDROME (P&S Industry Clinical Trial)

    Jan 17 2014 - Jan 17 2019

    MITOCHONDRIAL ENCEPHALOMYOPATHIES AND MENTAL RETARDATION (Federal Gov)

    Dec 1 1996 - Feb 29 2016

    SMA FOUNDATION CENTER GRANT (Private)

    Jul 1 2015 - Dec 31 2015

    PEDIATRIC NEUROMUSCULAR CLINICAL RESEARCH NETWORK FOR SMA (Private)

    Jul 1 2012 - Jun 30 2015

    GENE THERAPY OF GLUT1 DEFICIENCY (Private)

    Jan 1 2012 - May 31 2015

    COLUMBIA SMA PROJECT: 4-AP AS A POTENTIAL SMA THERAPEUTIC AGENT AND BIOLOGICAL MECHANISMS OF ACTION (Federal Gov)

    Sep 1 2011 - Aug 31 2014

    COLUMBIA SMA PROJECT: A RANDOMIZED, CONTROL TRIAL OF THE EFFECTS OF EXERCISE ON MOTOR FUNCTION AND STRENGTH IN PATIENTS WITH SPINAL MUSCULAR ATROPHY (SMA) (Federal Gov)

    May 3 2010 - May 2 2014

    GIBLIN RESEARCH FUND FOR PEDIATRIC NEUROLOGY (Private)

    Jul 1 1994 - Dec 31 2013

    PEDIATRIC NEUROMUSCULAR CLINICAL RESEARCH (Private)

    Jul 1 2004 - Jun 30 2012

    PEDIATRIC NEUROMUSCULAR CLINICAL RESEARCH NETWORK (Private)

    Jul 1 2004 - Jun 30 2012

    PEDIATRIC NEUROMUSCULAR CLINICAL RESEARCH NETWORK FOR SPINAL MUSCULAR ATROPHY CLINICAL TRIALS (Private)

    Jul 1 2004 - Jun 30 2012

    NEUROLOGICAL SCIENCES ACADEMIC DEVELOPMENT AWARD (NSADA) (Federal Gov)

    Jul 1 1993 - Jun 30 2011

    NEWBORN SCREENING STUDY FOR CARNITINE DEFICIENCY (Private)

    Jul 1 1999 - Jun 30 2005