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Guy M. McKhann II, MD

  • Associate Professor of Neurological Surgery at CUMC
Guy M. McKhann II, MD

Dr. McKhann graduated Phi Beta Kappa and Magna Cum Laude from Duke University, with Research Honors for his investigations into brain tumor immunobiology. He attended Yale School of Medicine where he was AOA, Cum Laude, a Farr Scholar, and one of five recipients of the medical school’s highest thesis award. Dr. McKhann trained in Neurological Surgery at the University of Washington, as well as Atkinson Morley’s Hospital in Wimbledon, England.

Dr. McKhann combines clinical skill and compassionate care to maximize patient outcomes. He treats patients with a variety of brain conditions including Brain Tumors, Epilepsy, Movement Disorders, Adult Hydrocephalus, Chiari Malformations, Cavernous Malformations, Trigeminal Neuralgia, and Neurotrauma. His areas of particular technical expertise include microneurosurgery, computer guided stereotactic neuronavigation, intraoperative awake brain mapping, neuroendoscopy, minimally invasive brain surgery, gamma knife radiosurgery, deep brain stimulation, and cerebrospinal fluid shunting.

Dr. McKhann also works as a translational neuroscientist, running a laboratory that investigates epileptic development and treatment. In addition he helps direct a multidisciplinary team that studies the mechanisms of brain plasticity, recovery, and repair. His basic and clinical research has been funded by the National Institutes of Health, the American Association of Neurological Surgeons, the Klingenstein Foundation, the Charles A. Dana Foundation, the New York Academy of Medicine, Parents Against Childhood Epilepsy, and the Irving Center for Clinical Research.

Departmental Appointments

  • Department of Neurological Surgery

Board Certifications

  • Neurological Surgery

Areas of Expertise

  • Neurosurgery
  • Brain & Spinal Tumors
  • Glioblastoma Multiforme
  • Gliomas
  • Hemangioblastoma
  • Hemifacial Spasm
  • Microvascular Decompression
  • Minimally Invasive (Endoscopic) Neurosurgery
  • Minimally Invasive Neurosurgery
  • Minimally Invasive Procedures
  • Minimally Invasive Spine Techniques
  • Neurofibromatosis
  • Neurological Surgery
  • Neurostimulation
  • Pediatric Epilepsy Surgery
  • Radiosurgery
  • Second Opinion
  • Stereotactic Neurosurgery
  • Stereotactic Surgery
  • Trigeminal Neuralgia Surgery
  • Vascular Malformation
  • Brain Tumor
  • Endoscopic Neurosurgery
  • Brain Abscess
  • Biopsies
  • Anaplastic Astrocytoma
  • Arachnoid Cyst
  • Craniotomy
  • Brain Cancer
  • Epilepsy Surgery
  • Meningioma
  • Benign Essential Tremor
  • Concussion
  • Trigeminal Neuralgia
  • Skull Base Surgery
  • Orbital Tumor
  • Movement Disorder
  • Dystonia
  • Adult Trauma
  • Astrocytoma
  • Cavernous Malformation
  • Stereotactic Radiosurgery
  • Skull Base Tumors
  • Hydrocephalus
  • Colloid Cyst of Third Ventricle
  • Brain Tumor Surgery
  • Seizure Disorder
  • Deep Brain Stimulation
  • Pineal Tumor
  • Minimally Invasive Brain Surgery
  • Microsurgery
  • Chiari Malformation
  • Functional Brain Mapping
  • Gamma Knife Radiosurgery
  • Shunts
  • Traumatic Brain Injury
  • Microvascular Neurosurgery
  • Cerebrospinal Fluid Conditions
  • Computer Assisted Surgery (CAS)
  • Parkinson's Disease
  • Head Injury

Education & Training

  • Yale University School of Medicine
  • Residency: University of Washington Medical Center
  • Fellowship: University of Washington Medical Center

Locations

  • Neurological Institute of New York

    710 West 168th Street
    Suite: 413
    New York, NY 10032
    Phone:
    (212) 305-0052
    For new and current patient appointments, call:
    (212) 305-0052
    Fax:
    (212) 305-3629

Centers/Institutes/Programs

  • Herbert Irving Comprehensive Cancer Center

Provider Affiliations

  • NewYork-Presbyterian/Columbia
  • NewYork-Presbyterian/Lawrence Hospital

Insurance Programs

Please contact the provider's office directly to verify that your particular insurance is accepted.

  • Aetna [EPO, HMO, NY Signature, POS, PPO, Signature Administrators, Student Health]
  • Cigna [EPO, Great West, HMO, POS, PPO]
  • Empire Blue Cross Blue Shield [Blue Priority, EPO, HMO, NYP Employee Plan, POS, PPO]
  • Oxford Health Plans [Freedom, Liberty]
  • UnitedHealthcare [Columbia University Employee Plan, EPO, HMO, POS, PPO]

This provider accepts new patients

Appointment Phone Number: (212) 305-0052

Research Interests

  • Astrocyte function in epilepsy
  • Brain organization of language and motor function
  • Adult hydrocephalus

NIH Grants

  • SEIZURE LOCALIZATION IN HUMANS: THE EFFECT OF INHIBITORY SUROUND ON THE EEG (Federal Gov)

    Sep 1 2013 - Jun 30 2018

    TARGETING THE MTOR PATHWAY IN GILOMA-ASSOCIATED EPILEPSY IN MICE AND HUMANS (Private)

    Sep 1 2015 - Aug 31 2017

    RADIOSURGERY VS LOBECTOMY FOR TEMPORAL LOBE EPILEPSY: PHASE 3 CLINICAL TRIAL (Federal Gov)

    Jun 1 2014 - May 31 2015

    RADIOSURGERY VS. LOBECTOMY FOR TEMPORAL LOBE EPILEPSY: PHASE 3 CLINICAL TRIAL (Federal Gov)

    Jun 1 2011 - May 31 2012

    ABERRANT ASTROCYTIC CONTROL OF NEURONAL EXCITABILITY IN TUBE ROUS SCLEROSIS: A POTENTIAL THERAPEUTIC TARGET IN TSC EPILEP (Private)

    Jul 1 2008 - Jun 30 2011

    HHMI FELLOWSHIP--REACTIVE GLIOSIS IN A RAT MODEL OF TEMPORAL LOBE EPILEPSY--CELLULAR LINEAGE AND ELECTROPHYSIOLOGIC... (Private)

    Jul 1 2007 - Jun 30 2008

    PLASTICITY IN THE MATURE BRAIN: PATTERNS OF CORTICAL REORGANIZATION FOLLOWING BRAIN LESION REMOVAL (Private)

    May 1 2001 - Jan 1 2008