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Matthew B. Harms, MD

  • Associate Professor of Neurology
Matthew B. Harms, MD

Matthew Harms, MD is an Assistant Professor of Neurology. Dr. Harms received his A.B. in Biology summa cum laude from Harvard University in 1997, and his medical doctorate from the University of California San Francisco in 2003. He remained at San Francisco for neurology residency and served as Chief Resident in his final year. Dr. Harms completed neuromuscular medicine and clinical neurophysiology fellowships under the mentorship of Dr. Alan Pestronk at Washington University in St. Louis. His clinical training in neuromuscular diseases led him into the laboratory of Dr. Robert Baloh, where his post-doctoral research identified the genes responsible for two orphan human diseases- dominant spinal muscular atrophy with lower extremity predominance and limb-girdle muscular dystrophy type 1D.

Dr. Harms joined the neuromuscular medicine faculty at Washington University in 2009 with board certifications in neurology, clinical neurophysiology, and neuromuscular medicine. In 2011, Dr. Harms assumed leadership of the Washington University Neuromuscular Genetics Project and established his research laboratory to continue harnessing emerging genetic technologies to understand the causes of inherited neuromuscular diseases. The lab focuses on diseases of the motor neuron, including amyotrophic lateral sclerosis, spinal muscular atrophy, and the hereditary motor neuropathies, and where his efforts have helped identify more than 5 novel disease genes. Here at Columbia, he will continue these efforts, directing an international multi-site effort using whole genome and transcriptome sequencing to bring precision medicine to amyotrophic lateral sclerosis. His laboratory efforts will occur in both the Motor Neuron Center and the Institute for Genomic Medicine.

Departmental Appointments

  • Department of Neurology
    Division of Neuromuscular Medicine

Board Certifications

  • Neuromuscular Medicine
  • Clinical Neurophysiology
  • Neurology

Areas of Expertise

  • ALS (Amyotrophic Lateral Sclerosis)
  • Clinical Research
  • Lou Gehrig's Disease
  • Metabolic Myopathy
  • Mitochondrial Diseases
  • Muscular Dystrophy
  • Myofibrillar Myopathy
  • Myopathy
  • Peripheral Neuropathy

Education & Training

  • MD, University of California San Francisco School of Medicine
  • Internship: University of California San Francisco Medical Center
  • Residency: University of California San Francisco Medical Center
  • Fellowship: Barnes Jewish Hospital/Washington University
  • Fellowship: Barnes Jewish Hospital

Locations

  • Neurological Institute of New York

    710 West 168th Street
    New York, NY 10032
    For new and current patient appointments, call:
    (212) 305-1319
    Fax:
    (212) 342-4536

Centers/Institutes/Programs

Provider Affiliations

  • NewYork-Presbyterian/Columbia

This provider accepts new patients

Appointment Phone Number: (212) 305-1319

Contact Info

NIH Grants

  • INTEGRATED GENOMICS IN CLINICAL ALS (Private)

    Oct 1 2015 - Sep 30 2018

    NEXT GENERATION SEQUENCING APPROACHES FOR NOVEL GENE DISCOVERY IN ALS (Federal Gov)

    Sep 1 2016 - Jun 30 2017

    EFFECT OF MEXILETINE ON CORTICAL HYPEREXCITABILITY IN SPORADIC AMYOTROPHIC LATERAL SCLEROSIS (SALS) (Private)

    Jan 1 2016 - Jun 30 2017

    MECHANISMS AND PHENOTYPES OF ALS CAUSED BY THE NOVEL ALS GENE TBK1 (Private)

    Dec 1 2015 - Nov 30 2016

    UNDERSTANDING CLINICAL PHENOTYPE AND COLLECTING BIOMARKER SAMPLES IN C9ORF72 ALS (Private)

    Nov 1 2015 - Oct 31 2016

    BIOGEN IDEC (Private)

    Nov 1 2014 - Oct 31 2015