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Hwamee Oh, PhD

  • Assistant Professor of Neuropsychology (in Neurology and in the Taub Institute for Research on Alzheimer's Disease and the Aging Brain)
Hwamee Oh, PhD

Dr. Hwamee Oh's research focuses on understanding neural and cognitive basis of memory, how it changes with normal aging and pathological aging associated with Alzheimer's disease, and individual difference factors contributing to the brain aging and cognition relationship.

Recent studies examined cognitive, structural, and functional alterations in preclinical older adults with β-amyloid deposition, a pathological hallmark of Alzheimer’s disease, with an overarching goal to identify early neural and cognitive markers in cognitively normal older adults harboring AD neuropathology.

Dr. Oh applies a cognitive neuroscience approach, multimodality neuroimaging methods of brain amyloid positron emission tomography (PET) and structural and functional magnetic resonance imaging (MRI), and neuropsychological tests in studying cognitive aging and aging with AD neuropathology.

Departmental Appointments

  • Department of Neurology
    Division of Cognitive Neuroscience

Education & Training

  • PhD, State University of New York - Stonybrook
  • Fellowship: University of California, Berkeley

Centers/Institutes/Programs

  • Taub Institute for Research on Alzheimer's Disease and the Aging Brain

Contact Info

Honors & Awards

The de Leon Prize in Neuroimaging: New Investigator Award, Alzheimer’s Association International Conference, Alzheimer’s Imaging Consortium, Copenhagen, Denmark. 2014.

Travel Scholarship Award, Alzheimer’s Association International Conference, Boston, MA. 2013.

Travel Scholarship Award, Alzheimer’s Imaging Consortium, preconference of Alzheimer’s Association International Conference, Boston, MA. 2013.

Alzheimer’s Association Award for Excellence in Alzheimer’s Research, Alzheimer’s Association Symposium, Stanford University, 2011.

UCLA Advanced Neuroimaging Summer School Fellowship, UCLA, 2009.

Departmental Retirees Dissertation Fellowship, SUNY-Stony Brook, 2008.

Grants

EXPLORING COGNITIVE AGING USING REFERENCE ABILITY NEURAL NETWORKS

2RF1AG038465-06

Role: Co-Investigator

Project Dates: Aug 1 2016 to June 30 2021

IMAGING OF COGNITION, LEARNING AND MEMORY IN AGING

5R01AG026158-10

Role: Co-Investigator

Project Dates: Sep 1 2011 to May 31 2021

NIH Grants

  • EXPLORING COGNITIVE AGING USING REFERENCE ABILITY NEURAL NETWORKS (Federal Gov)

    Aug 1 2016 - Jun 30 2021

    IMAGING OF COGNITION, LEARNING AND MEMORY IN AGING (Federal Gov)

    Sep 1 2011 - May 31 2017

    EXERCISE, AGING, AND COGNITION: EFFECT AND MECHANISMS (Federal Gov)

    Aug 1 2010 - May 31 2017

Publications

Hwamee Oh, Cindee M. Madison, Suzanne L. Baker, Gil Rabinovici, William J. Jagust (2016). Dynamic relationships between age, β-amyloid deposition, and glucose metabolism link to the regional vulnerability to Alzheimer’s disease. Brain, [Advance Access]

Hwamee Oh, Jason Steffener, Qolamreza R. Razlighi, Christian Habeck, Yaakov Stern (2016). Beta-amyloid deposition is associated with decreased right prefrontal activation during task switching among cognitively normal elderly. The Journal of Neuroscience, 36(6), 1962-70.

Hwamee Oh, Jason Steffener, Qolamreza R. Razlighi, Christian Habeck, Dan Liu, Yunglin Gazes, Sarah Janicki, Yaakov Stern (2015). Aβ-related hyperactivation in frontoparietal control regions in cognitively normal elderly. Neurobiology of Aging, 36(12), 3247-54.

*Jeremy Elman, *Hwamee Oh, Cindee M. Madison, Suzanne L. Baker, Jacob W. Vogel, Shawn M. Marks, Sam Crowley, James P. O’Neil, William J. Jagust (2014). Neural compensation in older people with brain Aβ deposition. Nature Neuroscience, 17(10): 1316-8. *Co-First authors

Hwamee Oh, Cindee Madison, Sylvia Villeneuve, Candace Markley, & William J. Jagust (2014). Association of gray matter atrophy with age, β-amyloid, and cognition in aging. Cerebral Cortex, 24(6): 1609-18.

Rik Ossenkoppele, Cindee Madison, Hwamee Oh, Miranka Wirth, Bart N. van Berckel, William J. Jagust (2014). Is verbal episodic memory in elderly with amyloid deposits preserved through altered neuronal function? Cerebral Cortex, 24(8):2210-8.

Hwamee Oh, Christian Habeck, Cindee Madison, & William J. Jagust (2014). Covarying patterns of Aβ deposition, glucose metabolism, and gray matter volume in cognitively normal elderly. Human Brain Mapping, 35(1): 297-308.

Hwamee Oh & William J. Jagust (2013). Frontotemporal network connectivity during memory encoding is increased with aging and disrupted by beta-amyloid. The Journal of Neuroscience, 33(47), 18425-37.

Trey Hedden, Hwamee Oh, Alayna P. Younger, and Tanu Patel (2013). Meta-Analysis of Amyloid-Cognition Relations in Cognitively Normal Older Adults. Neurology, 80(14), 1341-8.

Miranka Wirth, Sylvie Villeneuve, Claudia M. Haase, Cindee M. Madison, Hwamee Oh, Susan M. Landau, Gil D. Rabinovici, William J. Jagust. (2013) Associations between Alzheimer disease biomarkers, neurodegeneration, and cognition in cognitively normal older people. JAMA neurology, 70(12):1512-9.

Miranka Wirth, Cindee M. Madison, Gil D. Rabinovici, Hwamee Oh, Susan M. Landau, William J. Jagust. (2013) Alzheimer's disease neurodegenerative biomarkers are associated with decreased cognitive function but not β-amyloid in cognitively normal older individuals. The Journal of Neuroscience, 33(13):5553-63

For a complete list of publications, please visit PubMed.gov