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Hans-Ulrich Klein, PhD

  • Assistant Professor of Neurological Sciences(in Neurology, the Taub Institute for Research on Alzheimer's Disease and the Aging Brain)
Hans-Ulrich  Klein, PhD

Dr. Hans-Ulrich Klein received his PhD in Biomedical Informatics and Biomathematics from the University of Münster, Germany, where he worked on models and algorithms to analyze and integrate epigenomic and transcriptomic data. Following an emerging interest in epigenetic mechanisms of aging and neurodegeneration, he joined the Ann Romney Center for Neurologic Diseases at Brigham and Women’s Hospital and Harvard Medical School as a research fellow in Dr. Philip De Jager’s laboratory, and subsequently continued his research fellowship here at the Taub Institute, prior to being recruited as a faculty member. Dr. Klein’s current research focuses on the interaction between the epigenome, transcriptome, genetic risk variants and neuropathologies in different cell types of the central nervous system, with the aim of understanding the pathogenesis of neurological diseases.

Departmental Appointments

  • Department of Neurology

NIH Grants

  • IDENTIFYING THE MOLECULAR SYSTEMS, NETWORKS, AND KEY MOLECULES THAT UNDERLIE COGNITIVE RESILIENCE (Federal Gov)

    Sep 15 2017 - May 31 2022

    PATHWAY DISCOVERY, VALIDATION AND COMPOUND IDENTIFICATION FOR ALZHEIMER S DISEASE (Federal Gov)

    Sep 20 2013 - Aug 31 2019

    RISK FACTORS, PATHOLOGY AND CLINICAL EXPRESSIONS OF AD (Federal Gov)

    Jul 1 2017 - Jun 30 2018

    TAU-SLICEOSOME INTERACTIONS IN ALZHEIMER S DISEASE (Federal Gov)

    Jun 1 2017 - Apr 30 2018

Publications

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