Jose Gutierrez-Contreras, MD, MPH
- Assistant Professor of Neurology
Dr. Gutierrez specializes in stroke prevention, treatment, and care. His interest is focused on the large arteries of the brain and the mechanisms underlying pathological changes in these arteries as a consequence of vascular risk factors such as high blood pressure, diabetes, high cholesterol and smoking. Because individuals with HIV might be at higher risk of stroke and dementia, Dr. Gutierrez has studied subjects with HIV to evaluate if vascular risk factors interact with HIV, or whether the medications given to treat HIV contribute to the development of brain arterial disease in this population. Understanding how vascular risk factors injure the brain arteries might lead to innovative ways to prevent strokes in the general population and in those with HIV.
Dr. Gutierrez's main research interest is brain arterial remodeling and its association/risks with cerebrovascular disease, including stroke and vascular dementia. His projects have specifically focused on HIV and the mechanism underlying the arteriopathy sometimes seen in HIV, consisting of arterial dilatation and subsequent strokes. Dr. Gutierrez is the leader of one of the largest postmortem brain large arteries studies from which morphometric and functional characterization has been carried over. Additionally, he has dedicated a fair amount of time to collecting brain arterial diameters in more than 700 stroke-free subjects from the Northern Manhattan Study (NOMAS), to further investigate the associations and consequences of brain arterial remodeling. Dr. Gutierrez’s other areas of interest include disparities in stroke mechanisms and stroke prevention.
- Department of Neurology
Division of Stroke and Cerebrovascular Disease
(in addition to English)
Education & Training
- MD, Universidad de Guadalajara
- Residency: Jackson Memorial Hospital
- Fellowship: NewYork-Presbyterian Hospital/Columbia University Medical Center
- 01/07/2012-06/30/2013: Postdoctoral research fellow, Department of Neurology, NewYork-Presbyterian Hospital
- 07/01/2012-06/30/2013: Assistant in Clinical Neurology, Department of Neurology, College of Physicians & Surgeons of Columbia University
1. “Cerebral Arterial Biology and Arterial Remodeling”, 36th Congress of Clinical Neuroscience, Guanajuato, Mexico, 15/05/2014. Role: Speaker.
2. “Brain Arterial Biology: Why should it matter?”, Department of Medicine Grand Rounds, Metropolitan Hospital Center, New York College of Medicine, New York, NY, USA, 01/30/2014. Role: Speaker.
3. HIV and brain atherosclerosis: results from the Brain Arterial Remodeling Study (BARS). Mount Sinai School of Medicine, July 2013. Role: Speaker.
4. ‘Large intracranial stenosis in the post-SAMPRISS era: Case presentation’. Brain Attack & Cerebrovascular Disease Update 2013. Role: Speaker.
5. ‘Contribution of HIV to brain arterial remodeling”. Department of Medicine Grand Rounds, Metropolitan Hospital Center, New York College of Medicine, New York, NY, USA, 01/31/2013. Role: Speaker.
6. ‘Contribution of HIV to brain arterial remodeling”. Department of Neurology Grand Rounds, Columbia University, New York, NY, USA, 10/10/2012. Role: Speaker.
7. ‘Presentation of Challenging Case Studies’. American Heart Association/American Stroke Association New York City Stroke Forum. New York, USA, 2011. Role: Speaker.
8. Anatomy and physiology of the respiratory system. CMN Siglo XXI, IMSS; México City, México, 2006. Role: Speaker.
9. Dyslipidemia and Diabetes: What to do? Colegio Mexicano de Medicina Interna; México city, México, 2006. Role: Speaker.
10. Alfa glucosidase inhibitors in diabetes control. National Diabetes Conference, México city, México, 2005. Role: Speaker
11. Raymundo: One of us. Ethical discussion. Hospital Gabriel Mancera, IMSS; México city, México, 2005. Role: Speaker.
12. Guillain-Barre symposium. Antiguo Hospital Civil de Belén; Guadalajara, México, 2004. Role: Speaker.
13. Neurological examination. Antiguo Hospital Civil de Belén; Guadalajara, México, 2004.
14. Epilepsy I.-Clinical manifestations. Antiguo Hospital Civil de Belén; Guadalajara, México, 2004. Role: Speaker.
15. Epilepsy II.-Classification. Antiguo Hospital Civil de Belén; Guadalajara, México, 2004. Role: Speaker.
16. Cerebral Palsy. Antiguo Hospital Civil de Belén; Guadalajara, México, 2004. Role: Speaker.
1. Stroke Warriors Meeting, Columbia University Community Center, New York, NY, USA. 08/10/2012. Goal: To educate the community of ways to live a healthier life. Time: 2 hours.
2. Stroke Warriors Meeting, Harlem Hospital Center, New York, NY, USA. 08/10/2012. Goal: To educate the community of ways to identify signs of stroke, cope with the consequences of stroke and strategize the post stroke recovery and secondary prevention. Time: 2 hours.
3. Manhattan HIV Brain bank, Community Advisory Board Meeting, Mount Sinai Hospital, New York, NY, USA. 07/25/2012. Goal:” To present HIV infected individuals with the methods and expected goal of neuroscience research to enhance participation and provide feedback to the community from where the brain donors come from. Time: 2 hours.
4. Ethics committee in Gabriel Mancera Hospital, IMSS, 03/2005-02/2006, Mexico City, Mexico.
5. Community service at CAIPNE organization: Helping children with Epilepsy, 02/2004-02/2005, Guadalajara, Mexico
• The American Association of French-speaking Health Professionals, 07/2007-current
• Americas Society/ Council of the Americas, 01/2013-current
• New York Medical Association, 10/2013-current
• New York Academy of Science, 04/2012-current
• American Medical Association, 04/2012-current
• American Heart Association, 01/01/2011-current
• American Academy of Neurology, 07/2008-current
• Alumni Association of New York Medical College, 06/2008-current
• Florida Society of Neurology, 07/2008-06/2011
• Mexican College of Internal Medicine, 03/2005-06/2007
Honors & Awards
- American Heart Association Clinical Research Program fellowship, 2012-2013
- Mount Sinai Summer Institute for NeuroAIDS Disparities (MSINAD) 2012 scholar
- Resident Research Award, 06/2011, University of Miami Miller School of Medicine, Miami, FL
- Resident-Clinician Researcher Track nominee, University of Miami, 07/2009, Miami, FL
- Performance award in residency program, 02/2006, Mexico City, Mexico
- Top class rank in medical school internship, 06/2003, Guadalajara, Mexico
- Top class rank in high school, 07/1998, Tamazula de Gordiano, Mexico
List Funding Source, Project Title & Number
Role in Project
American Heart Association
“Contribution of HIV infection to intracranial vascular remodeling: a case –control study”
List Funding Source, Project Title & Number
Role in Project
“Mount Sinai Summer Institute for NeuroAIDS Disparities (MSINAD) 2012 scholar grants” #5R25MH080663-05(PI S. Morgello)
GENETIC CONTRIBUTION TO BRAIN ARTERIAL DILATATION AND ITS ROLE IN COGNITION AND DEMENTIA (Federal Gov)
May 1 2018 - Jun 30 2023
LONG-TERM OUTCOME IN UNRUPTURED BRAIN ARTERIOVENOUS MALFORMATION PATIENTS (Federal Gov)
May 15 2017 - Apr 30 2022
WHICAP -GENETIC EPIDEMIOLOGY OF CEREBROVASCULAR FACTORS IN ALZHEIMER S DISEASE (Federal Gov)
Aug 1 2016 - Jun 30 2021
OFFSPRING STUDY OF MECHANISMS OF RACIAL DISPARITIES IN ALZHEIMER S DISEASE (Federal Gov)
Sep 1 2016 - Mar 31 2021
WHITE MATTER HYPERINTENSITIES IN AGING AND DEMENTIA (Federal Gov)
Sep 30 2016 - Aug 31 2019
CAROTID REVASCULARIZATION AND MEDICAL MANAGEMENT FOR ASYMPTOMATIC CAROTID STENOSIS TRIAL - HEMODYNAMICS (CREST-H) (Federal Gov)
May 15 2017 - Apr 30 2018
ARTERIAL WALL INFECTION BY HIV AS A TRIGGER FOR ARTERIAL WALL INFLAMMATION (Private)
Jan 1 2016 - Dec 31 2016
AIDS CLINICAL TRIALS GROUP (ACTG) (Federal Gov)
Jul 1 2016 - Nov 30 2016
NEW YORK COLUMBIA COLLABORATIVE SPOTRIAS (Federal Gov)
Aug 1 2010 - Jul 31 2016
STROKE INCIDENCE AND RISK FACTORS IN A TRI-ETHNIC REGION (Federal Gov)
Sep 30 2015 - Dec 31 2015
CONTRIBUTION OF HIV INFECTION TO INTRACRANIAL VASCULAR REMODELING: A CASE CONTROL STUDY (Private)
Jan 1 2013 - Dec 31 2015
THE MOUNT SINAI INSTITUTE FOR NEUROAIDS DISPARITIES (Federal Gov)
Jun 18 2012 - Apr 30 2014
1. Gutierrez J, Rosoklija G, Murray J, Chon C, Elkind MSV, Goldman J, Honig L, Dwork AJ, Morgello S, Marshall RS. A quantitative perspective to the study of brain arterial remodeling of donors with and without HIV in the Brain Arterial Remodeling Study (BARS). Front Physiol (2014). 5 (56). [Epub ahead of print]doi: 10.3389/fphys.2014.00056
2. Gutierrez J, Williams O. A decade of racial and ethnic stroke disparities in the US. Neurology (2013). In press.
3. Gutierrez J, Elkind MSV, Rundek T, Sacco RL, Wright CB. Perivascular spaces are associated with atherosclerosis: an insight from the Northern Manhattan Study. AJNR Am J Neuroradiol (2013). Apr 4. 34(9):1711-6.
4. Gutierrez J, Elkind MSV, Marshall RS. Cardiovascular profile and events of US adults 20-49 years old and HIV status: NHANES 1999-2008. AIDS care (2013). Feb 21. [Epub ahead of print]
Gutierrez J, Bagci A, Gardener H, Rundek T, DeCarli C, Elkind MSV, Alperin N, Sacco RL, Wright CB. Dolichoectasia diagnostic methods in a multi-ethnic, stroke-free cohort: Results from the Northern Manhattan Study. J Neuroimaging (2013). Jan 14. doi: 10.1111/j.1552-6569.2012.00781.x. [Epub ahead of print
5. Gutierrez J, Ramirez G, Rundek T, Sacco RL. Statin Therapy in the Prevention of Recurrent Cardiovascular Events: A Sex-Based Meta-analysis. Arch Intern Med. (2012) 172:909-919.
6. Gutierrez J, Sacco RL, Wright CB. Dolichoectasia-an evolving arterial disease. Nat Rev Neurol (2011). 7, 41-50.
7. Gutierrez J, Glenn M, Isaacson RS, Marr DA, Mash D, Petito C. Thinning of the arterial media layer: a possible preclinical stage in HIV vasculopathy. Stroke. (2012) 43:1156-1158.
For a complete list of publications, please visit PubMed.gov