Search Site

Roy N. Alcalay, MD, MS

  • Florence Irving Assistant Professor of Neurology (in the Taub Institute on Alzheimer's Disease and the Aging Brain)
Roy N. Alcalay, MD, MS

Roy Alcalay is an assistant professor of neurology at the Taub Institute and the program director of the Movement Disorders Fellowship at the Columbia University Medical Center. He obtained his medical degree from Tel Aviv University, Israel, his neurology training from the Harvard University residency program at Massachusetts General Hospital and Brigham and Women’s Hospital and his movement disorders training at Columbia University. He is a graduate of the Patient Oriented Research and earned Master’s in biostatistics from Columbia University. His research focuses on biomarkers and genetics in Parkinson’s disease and cognitive functioning. He is a Brookdale Leadership in Aging fellow, and his research is supported by the NIH, the Parkinson’s Disease Foundation, the Michael J Fox Foundation and the Smart Foundation.

His clinical practice focuses on Parkinson's disease and other movement disorders, including tremor, dystonia, Tourette syndrome, myoclonus, ataxia and chorea. 

Dr. Alcalay's primary research work involves the genetics and the epidemiology of Parkinson's disease. His research is supported by the National Institute of Health (NIH), the Brookdale Foundation, the Parkinson's Disease Foundation, the Michael J Fox Foundation and the Smart Foundation.

Columbia's movement disorders fellowship director, Dr. Alcalay is also a member of the American Academy of Neurology and of the Movement Disorder Society, Dr. Alcalay has contributed to a range of original articles in leading medical research journals, including the The New England Journal of Medicine, Neurology, Archives of Neurology, Genetics in Medicine, Journal of Clinical and Experimental Neuropsychology, Movement Disorders and Parkinsonism and Related Disorders.

Departmental Appointments

  • Department of Neurology
    Division of Movement Disorders

Board Certifications

  • Neurology

Areas of Expertise

  • Parkinson's Disease
  • Movement Disorder

Languages Spoken

(in addition to English)

  • Hebrew
  • French

Education & Training

  • Tel-Aviv University School of Medicine
  • Residency: Massachusetts General Hospital

Locations

  • Neurological Institute of New York

    710 West 168th Street
    New York, NY 10032
    Phone:
    (212) 305-5554
    For new and current patient appointments, call:
    (212) 305-1303
    Fax:
    (212) 305-1304

Provider Affiliations

  • NewYork-Presbyterian/Columbia

Insurance Programs

Please contact the provider's office directly to verify that your particular insurance is accepted.

  • Aetna [EPO, HMO, Medicare Managed Care, NY Signature, POS, PPO, Signature Administrators, Student Health]
  • Affinity [Access (Exchange), Essential Plan, Medicaid Managed Care, Medicare Managed Care]
  • Amida Care [Special Needs Plan]
  • Cigna [EPO, Great West, HMO, POS, PPO]
  • Emblem/HIP [ConnectiCare, EPO, Essential Plan, HMO, Medicaid Managed Care, Medicare Managed Care, POS, PPO, Select Care (Exchange), Vytra]
  • Empire Blue Cross Blue Shield [Blue Priority, EPO, HMO, Medicare (Mediblue), NYP Employee Plan, Pathway (Exchange), POS, PPO]
  • Empire Blue Cross Blue Shield HealthPlus [Child/Family Health Plus, Essential Plan, Medicaid Managed Care]
  • Fidelis Care [Child/Family Health Plus, Medicaid Managed Care, Medicare Managed Care]
  • Healthfirst [Child/Family Health Plus, Medicaid Managed Care, Medicare Managed Care]
  • Local 1199 [Local 1199]
  • MagnaCare [MagnaCare]
  • Multiplan [Multiplan]
  • Oxford Health Plans [Freedom, Liberty, Medicare Managed Care]
  • POMCO [POMCO]
  • UnitedHealthcare [Columbia University Employee Plan, EPO, Essential Plan, HMO, Medicaid (Community Plan), Medicare Managed Care, POS, PPO]
  • VNSNY CHOICE [Medicare Managed Care, SelectHealth]
  • WellCare [Medicaid Managed Care, Medicare Managed Care]

This provider accepts new patients

Appointment Phone Number: (212) 305-1303

Lab Locations

  • Neurological Institute of New York

    710 West 168th Street
    New York, NY 10032
    Phone:
    (212) 305-5554
    Fax:
    (212) 305-1304

Contact Info

  • Office Phone: 212-305-5548

Research Interests

  • Biomarkers, genetic and epidemiology of Parkinson's disease

Grants

K02 award
9/1/12-8/31/17
NIH (1K02NS080915)
The role of glucocerebrosidase in Parkinson’s disease
Description: This study will provide information on the link between GBA mutations and Parkinson, including the magnitude of the risk of PD in mutation carriers and the mechanisms mediating this risk.

The Parkinson’s Disease Foundation (Alcalay PI)
7/1/11-present
Plasma Biomarkers in Parkinson’s Disease.
Description: the PDF supports biobanking DNA and plasma samples from PD cases and controls
http://www.pdf.org/en/research_alcalay

The Michael J Fox Foundation (Marder/Bressman/Giladi)
7/1/10 - 06/29/15                       
Parkinson’s Disease, Ashkenazi Jews and LRRK2: A consortium                              
This is a 3 site consortium designed to determine the phenotypic characteristics of LRRK2 carriers, the penetrance of LRRK2 in Ashkenazi, and genetic modifiers of LRRK2 including expression data.
https://www.michaeljfox.org/foundation/researchers.php?id=1259

The Michael J Fox Foundation (Alcalay, PI)
2/16/12-2/15/14
Neuropathological tissue collection in LRRK2 mutation carriers with and without Parkinson’s disease.
Description: this international collaboration aims to collect store and report pathological findings from LRRK2 mutation carriers and their family members with and without PD
https://www.michaeljfox.org/foundation/researchers.php?id=1259

The Irving Insitute, Columbia University
7/1/2012-6/30/2015
The role of glucocerebrosidase in Parkinson disease

The Michael J Fox Foundation (Un Kang, PI; Alcalay, site PI)
11/1/2012-10/31/2014    
Biofind: Biomarkers discovery cohort.  https://www.michaeljfox.org/foundation/researchers.php?id=1259

Past:

Patient Oriented Research Master’s Program
7/1/08-6/30/10
NIH: UL1 RR024156 from the National Center for Research Resources (NCRR)
This is a two year biostatistics Master’s program at Columbia University supported through the CTSA

K12 award
11/1/10-6/30/11
NIH (KL2 RR024157)
The role of glucocerebrosidase in Parkinson’s disease and cognitive impairment.

Brookdale Leadership in Aging Fellowship
07/01/10-08/31/12
The role of glucocerebrosidase in Parkinson’s disease and cognitive impairment.
This is a two-year fellowship which aims to establish the recipients in an area of aging research. (PI, support was “frozen” while on K12 award, and ceased when K02 was awarded).
http://www.brookdalefoundation.org/leadership/fellows/Alcalaybio.html

NIH Grants

  • COLUMBIA PBMC TECHNICIAN: PBMC CONSORTIUM AND ADDITIONAL LRRK2 AND NON-LRRK2 PBMC/NEUTROPHIL CUMC FULFILLMENT SUPPORT (Private)

    Jul 1 2017 - Jun 30 2018

    ANALYSIS OF GBA-RELATED BIOMARKERS IN PARKINSON S DISEASE (Private)

    Mar 1 2017 - Feb 28 2018

    DEVELOPING A TETRAMER LIBRARY AS A BIOMARKER FOR AUTOIMMUNITY IN PARKINSON S DISEASE (Private)

    Jun 14 2016 - Dec 31 2017

    PBMC AND URINE EXOSOSMES IN LRRK2 AND IDIOPATHIC PD (Private)

    Jan 1 2016 - Dec 31 2017

    NEUROINFLAMMATION VIA T-CELL RESPONSE IN PARKINSON S AND LEWY BODY DISEASES (Private)

    Jan 1 2016 - Dec 31 2017

    THE ROLE OF GLUCOCEREBROSIDASE IN PARKINSON S DISEASE (Federal Gov)

    Sep 1 2012 - Aug 31 2017

    PARKINSON S DISEASE FOUNDATION (PDF) RESEARCH CENTER GRANT (Private)

    Jul 1 2016 - Jun 30 2017

    ANALYSIS AND REPLICATION OF A GENETIC INTERACTION BETWEEN LRRK2 AND PARK16 (Private)

    Oct 2 2013 - Jul 31 2016

    PARKINSONS DISEASE FOUNDATION RESEARCH CENTER GRANT (Private)

    Jul 1 2000 - Jun 30 2016

    PENETRANCE OF LRRD2 IN THE MJ FOX LRRK2 COHORT CONSORTIUM (Private)

    Sep 18 2013 - Sep 17 2015

    PARKINSON S DISEASE, ASHKENAZI JEWS AND LRRK2: A CONSORTIUM PROPOSAL (Private)

    Jul 1 2011 - Jun 30 2015

    PARKINSONS DISEASE FOUNDATION RESEARCH CENTER GRANT (Private)

    Jul 1 2000 - Jun 30 2015

    FOX INVESTIGATION FOR NEW DISCOVERY OF BIOMARKERS, BIOFIND (Private)

    Nov 12 2012 - Jul 11 2014

    PARKINSON S DISEASE FOUNDATION RESEARCH CENTE (Private)

    Jul 1 2000 - Jun 30 2014

    PARKINSON S DISEASE FOUNDATION RESEARCH CENTE (Private)

    Jul 1 2000 - Jun 30 2014

    NEUROPATHOLOGICAL TISSUE COLLECTION IN LRRK2 MUTATION CARRIERS WITH AND WITHOUT PARKINSON S DISEASE (Private)

    Feb 16 2012 - Feb 15 2014

    PARKINSON''S DISEASE FOUNDATION RESEARCH CENTER GRANT-CLINICA L CORE (Private)

    Jul 1 2000 - Jun 30 2013

    THE ROLE OF GLUCOCEREBROSIDASE IN PARKINSON DISEASE AND COGN ITIVE IMPAIRMENT (Private)

    Jul 1 2010 - Aug 31 2012

Lab Members

  • Adina Wise, Research Assistant