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Randolph S. Marshall, MD, MS

  • Elisabeth K. Harris Professor of Neurology at Columbia University Medical Center
  • Chief, Stroke and Cerebrovascular Diseases
Randolph S. Marshall, MD, MS

Randolph Marshall, M.D., M.S. is the Elisabeth K Harris Professor of Neurology at Columbia University College of Physicians and Surgeons in New York City, Chief of the Stroke Division, and Attending Neurologist on the Stroke Service at New York Presbyterian Hospital. Dr. Marshall received his undergraduate degree from Harvard College in 1982, and his master's and medical degree from the University of California in 1988. After completing his Neurology Residency at Columbia-Presbyterian Hospital he completed 2 years of a Cerebrovascular fellowship with Dr. J.P. Mohr at the Neurological Institute at Columbia-Presbyterian Medical center, then joined the faculty of Columbia College of Physicians and Surgeons in 1994.

Dr. Marshall has a clinical practice in Neurology with a focus on cerebrovascular diseases and stroke. He is the also the program director for Columbia's Neurovascular Postdoctoral Fellowship.

Dr. Marshall co-directs the Richard & Jenny Levine Cerebral Localization Laboratory with Dr. Ronald M. Lazar, Ph.D, and conducts an active clinical research program on cerebral hemodynamics and brain function including the investigation of brain reorganization after stroke using function MRI. He has been continuously funded by NIH grants for his research since his appointment at Columbia College of Physicians and Surgeons in 1994. Current NIH grants include a program project—the Columbia Collaborative Specialized Program of Translational Research in Acute Stroke (SPOTRIAS—and an RO1 grant to study the correlation between cerebrovascular hemodynamics and cognitive function in patients with carotid artery stenosis. He also participates in several clinical trials for acute stroke therapy, stroke prevention and stroke recovery.

Departmental Appointments

  • Department of Neurology
    Division of Stroke and Cerebrovascular Disease

Languages Spoken

(in addition to English)

  • Spanish

Education & Training

  • University of California San Francisco School of Medicine
  • Internship: New York Hospital-Cornell Medical Center
  • Residency: Columbia Presbyterian Medical Center, NY
  • Fellowship: Columbia Presbyterian Medical Center, NY

Presentations

2008   “Rehabilitation Approaches to Aphasia” 6th World Stroke Congress, Vienna, Austria
2008   “Stroke Treatment: Update 2008” American College of Physicians, New Hampshire
2009   “Special Considerations in Acute Stroke Intervention: Treatment windows, clinical worsening, hemodynamics” Cardiology Grand Rounds, Beaumont Hospital, Royal Oak, MI
2009   “Carotid Artery Disease: Natural History, risk, and treatment implications” Cardiology Grand Rounds, Beaumont Hospital, Royal Oak, MI
2010   “Functional Imaging of Stroke Recovery,” San Antonio, TX (sponsored by Ferrer International)
2010   “The Case for Very Early Stroke Rehabilitation” ASNR meeting (symposium chair), Montreal

2011   “Stroke and Rehabilitation” Am Acad Neurol, Honolulu, HI2012   “The Case for Very Early Stroke Rehabilitation” AHA International Stroke Conference, New Orleans

2012   “Stroke Therapeutics” American Academy of Neurology, New Orleans
2013   “Cerebral Hemodynamics and Blood Pressure Management.” Longwood Medical, Harvard, Boston
2013   “Pumps, Aqueducts and Drought Management: Lessons in Cerebral Hemodynamics”, MGH, Boston
2013   “Hemodynamics in Acute Stroke Management Including Collaterals” Cardiology Research Foundation, San Francisco
2014   “Update on Stroke Management” NYPH Retreat, Palm Beach

2014   “Collateral Consequences in Large Vessel Disease” Second International Symposium on Collaterals in Stroke, UCLA
2014  “Hemodynamic Ischemia” Brain Ischemia and Stroke (Euro J Neurosci meeting), Rome, Italy

Committees/Societies/Memberships

  • American Academy of Neurology -- Science Committee
  • American Heart Association -- Stroke Council
  • American Medical Association

Honors & Awards

2013  C Miller Fisher lectureship, MGH, Boston

NIH Grants

  • NIH STROKE NET NATIONAL COORDINATING CENTER - ADMINISTRATIVE COLLABORATING AGREEMENT (Federal Gov)

    Sep 30 2013 - Jul 31 2018

    NIH STROKENET NATIONAL CLINICAL COORDINATING CENTER MASTER TRIAL AGREEMENT (Federal Gov)

    Sep 30 2013 - Jul 31 2018

    NEW YORK STROK TRIALS NETWORK OF COLUMBIA AND CORNELL (NYCCSTN) (Federal Gov)

    Sep 30 2013 - Jul 31 2018

    CEREBRAL HEMODYNAMICS AND NEUROCOGNITION IN SEVERE AORTIC VALVE DISEASE (Federal Gov)

    Aug 1 2016 - May 31 2018

    BLOOD FLOW AND COGNITION IN ASYMPTOMATIC CAROTID ARTERY DISEASE (Federal Gov)

    Apr 1 2012 - Mar 31 2018

    WHITE MATTER HYPERINTENSITIES IN AGING AND DEMENTIA (Federal Gov)

    Sep 30 2016 - Aug 31 2017

    DYNAMIC CEREBRAL AUTOREGULATION IN POSTPARTUM PREECLAMPSIA: A PILOT STUDY (Private)

    Jul 1 2016 - Jun 30 2017

    CAROTID REVASCULAIZATION AND MEDICAL MANAGEMENT FOR ASYMPTOMATIC CAROTID STENOSIS TRIAL (CREST-2) TRIAL ( (Federal Gov)

    Mar 1 2015 - Feb 28 2017

    NEW YORK COLUMBIA COLLABORATIVE SPOTRIAS (Federal Gov)

    Aug 1 2010 - Jul 31 2016

    GENETIC DETERMINANTS OF COLLATERAL STATUS IN STROKE - THE GENEDCSS STUDY (Private)

    Jun 16 2015 - Jun 15 2016

    MINORITIES WITH ICH (Federal Gov)

    Jul 1 2010 - Jun 30 2015

    THE MOUNT SINAI INSTITUTE FOR NEUROAIDS DISPARITIES (Federal Gov)

    Jun 18 2012 - Apr 30 2014

    UCLA SPOTRIAS CENTER APPLICATION (Federal Gov)

    Jun 1 2005 - Apr 30 2013

    CAROTID OCCLUSION SURGERY STUDY - COSS (Federal Gov)

    Dec 1 2007 - Nov 30 2012

    STUDY OF CAROTID OCCLUSION AND NEUROCOGNITION (RECON) (Federal Gov)

    Dec 6 2004 - Nov 30 2012

Publications

Marshall RS, Zarahn E, Alon L, Minzer B, Lazar RM, Krakauer JW. Early imaging correlates of subsequent motor recovery after stroke. Ann Neurol 2009, 65(5):596-602.

Carrera E, Lee LK, Giannacopoulos S, Marshall RS, Cerebrovascular Reactivity and Cerebral Autoregulation in Normal Subjects, J Neurol Sci 2009;285(1-2):191-4

Carrera E, Kurtz P, Badjatia N, Fernandez L, Claasen J, Lee K, Schmidt JM, Connolly ES, Marshall RS, Mayer SA. Cerebrovascular CO2 Reactivity and Delayed Cerebral Ischemia after Subarachnoid Hemorrhage. Arch Neurol 2010, 67:434-9.

Lazar RM, Berman MF, Festa JR, Geller AE, Matejovsky TG, Marshall RS. GABAergic but not anti-cholinergic agents re-induce clinical deficits after stroke. J Neurol Sci 2010;292(1-2):72-6.

Marshall RS and RM Lazar. Pumps, aqueducts and drought management: vascular physiology in vascular cognitive impairment. Stroke. 2011;42:221-6. PMID: 21148438

Willey JZ, Stillman J, Rivolta JA, Vieira J, Doyle MM, Linares G, Marchidann A, Elkind MSV, Boden-Albala B, Marshall RS. “Too Good to Treat”? Outcomes in patients not receiving thrombolysis due to mild deficits or rapidly improving symptoms. Int J Stroke 2012 Apr;7(3):202-6; [2011 Nov 22 epub ahead of print]. PMID: 22103880

Giannopoulos S, Katsanos AH, Tsivgoulis G, Marshall RS, Statins and Cerebral Hemodynamics, JCBFM 2012 Aug 29. doi: 10.1038/jcbfm.2012.122. [Epub ahead of print] PMID:22929438

Marshall RS , Festa JR , Cheung YK, Chen R, Pavol MA, Derdeyn CP, Clarke WR, Videen TO, Grubb RL, Adams HP, Powers WJ, Lazar RM. Cerebral hemodynamics and Cognitive Impairment; baseline data from the RECON trial. Neurology 2012 Jan 24;78(4):250-5. Epub 2012 Jan 11 PMID:  22238418

Marshall RS. Effects of altered cerebral hemodynamics on cognitive function. J Alzheimer’s Dis  2012; 32(3):633-42. doi: 10.3233/JAD-2012-120949.PMID:    22842868

For a complete list of publications, please visit PubMed.gov