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NeuroNEXT: Network for Excellence in Neuroscience Clinical Trials at Columbia

The Network for Excellence in Neuroscience Clinical Trials, or NeuroNEXT, was created to conduct studies of treatments for neurological diseases through partnerships with academia, private foundations, and industry. The network is designed to expand the National Institute of Neurological Disorders and Stroke's (NINDS) capability to test promising new therapies, increase the efficiency of clinical trials before embarking on larger studies, and respond quickly as new opportunities arise to test promising treatments for people with neurological disorders. The NeuroNEXT program aims to:

  • Provide a robust, standardized, and accessible infrastructure to facilitate rapid development and implementation of protocols in neurological disorders affecting adult and/or pediatric populations.
  • The network includes multiple Clinical Sites, one Clinical Coordinating Center (CCC) and one Data Coordinating Center (DCC).
  • Support scientifically sound, possibly biomarker-informed, Phase II clinical trials that provide data for clear go/no-go decisions.
  • Energize and mobilize federal, industry, foundations and patient advocacy partners by leveraging existing relationships between NINDS and NeuroNEXT to organize high impact Phase II clinical trials for neurological disorders.
  • Expand the pool of experienced clinical investigators and research staff who are prepared to be leaders of multicenter clinical research trials.

Our Team

NeuroNEXT News

Current NeuroNEXT studies:

Join the CUMC-WCMC NeuroNEXT Network

Columbia-Weill Cornell is establishing a network of affiliate neurologists/neurosurgeons and organizations to participate in NeuroNEXT studies. As a NeuroNEXT affiliate, you will receive occasional e-mails about upcoming clinical trials and events.

How to Submit a Proposal?

Develop an idea and call one of our team members. We will be happy to guide you through the process to complete the Clinical Study Concept Synopsis. For more information, visit


  • A webinar is a presentation by the PI to discuss his protocol that is getting ready for submission and to get feedback for improvement. Please check back for more information
  • A Brainstorming Session is a forum for specialists to discuss research priorities and to develop new NeuroNEXT proposal ideas. Please check back for more information.
  • Events Archive